Article
Invasion of Epithelial Cells by Locus of Enterocyte Effacement-Negative EnterohemorrhagicEscherichia coli
21 Apr 2005
Abstract excerpt
The majority of enterohemorrhagic Escherichia coli (EHEC) strains associated with severe disease carry the locus of enterocyte effacement (LEE) pathogenicity island, which encodes the ability to induce attaching and effacing lesions on the host intestinal mucosa. While LEE is essential for colonization of the host in these pathogens, strains of EHEC that do not carry LEE are regularly isolated from patients with...
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