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Enteropathogenic and enterohaemorrhagic Escherichia coli deliver a novel effector called Cif, which blocks cell cycle G2/M transition.

Molecular microbiology - 1 Dec 2003

Marchès Olivier, Ledger Terence Neil, Boury Michèle, Ohara Masaru, Tu Xuanlin, Goffaux Frédéric, Mainil Jacques, Rosenshine Ilan, Sugai Motoyuki, De Rycke Jean, Oswald Eric

Abstract excerpt

Enteropathogenic Escherichia coli (EPEC) and enterohaemorrhagic E. coli (EHEC) are closely related pathogens. Both use a type III secretion system (TTSS) encoded by the 'locus of enterocyte effacement' (LEE) to subvert and attach to epithelial cells through the injection of a repertoire of effector molecules. Here, we report the identification of a new TTSS translocated effector molecule called Cif, which blocks...

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PMID: 14651638
DOI: 10.1046/j.1365-2958.2003.03821.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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