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Article

Muscle atrophy induced by SOD1G93A expression does not involve the activation of caspase in the absence of denervation

24 Jan 2011

Abstract excerpt

BACKGROUND: The most remarkable feature of skeletal muscle is the capacity to adapt its morphological, biochemical and molecular properties in response to several factors. Nonetheless, under pathological conditions, skeletal muscle loses its adaptability, leading to atrophy or wasting. Several signals might function as physiopathological triggers of muscle atrophy. However, the specific mechanisms underlying the...

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PMID: 21798081
DOI: 10.1186/2044-5040-1-3

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