Article
The spectrum of beta-thalassemia mutations in the 22 Arab countries: a systematic review.
Expert review of hematology - 1 Jan 2021
Khan Aisha Moeen, Al-Sulaiti Asma Mohammed, Younes Salma, Yassin Mohamed, Zayed Hatem
Abstract excerpt
OBJECTIVES: To investigate the mutational spectrum in the HBB gene in Arab patients with β-thal. METHODS: Authors searched five databases (PubMed, Science Direct, Scopus, Web of Science, and Google Scholar) from the time of inception until March 2020. RESULTS: The authors search strategy yielded 3,229 citations, of which 48 eligible studies captured. 105 mutations were captured, of these, 99 were shared between...
Topics
- Arabs
- Gene Frequency
- Hemoglobins, Abnormal
- Humans
- Mutation
- Polymorphism, Single Nucleotide
- beta-Globins
- beta-Thalassemia