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Article

Human cutaneous melanomas lacking MITF and melanocyte differentiation antigens express a functional Axl receptor kinase.

The Journal of investigative dermatology - 1 Dec 2011

Sensi Marialuisa, Catani Mara, Castellano Giancarlo, Nicolini Gabriella, Alciato Federica, Tragni Gabrina, De Santis Giuseppina, Bersani Ilaria, Avanzi Giancarlo, Tomassetti Antonella, Canevari Silvana, Anichini Andrea

Abstract excerpt

Axl, a member of the TAM (Tyro3, Axl, Mer) family of receptor tyrosine kinases, displays an increasingly important role in carcinogenesis. Analysis of 58 cutaneous melanoma lines indicated that Axl was expressed in 38% of them, with significant overrepresentation in NRAS- compared with BRAF-mutat...

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Source

Identifiers

PMID: 21796150
DOI: 10.1038/jid.2011.218

Genes

MITF
BRAF
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21796150-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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