Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metabolic Alterations in Highly Tumorigenic Glioblastoma Cells

28 Jul 2011

Abstract excerpt

Recent studies suggest that a small subpopulation of malignant cells with stem-like properties is resistant to chemotherapy and may be responsible for the existence of residual cancer after treatment. We have isolated highly tumorigenic cancer cells with 100-fold increase in tumor initiating capacity from the tumor xenografts of human glioblastoma U87 cells in mice. These cells exhibit stem-like properties and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer, Hypoxia, and Metabolism
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21795717
DOI: 10.1074/jbc.m111.260935

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Metabolic Alterations in Highly Tumorigenic Glioblastoma CellsPMID 21795717Read ↗

Hallmarks of cancer stem cell metabolismSemantic proximity Read ↗

Effective Elimination of Cancer Stem Cells By a Novel Drug Combination StrategySemantic proximity Read ↗

Cancer Stem Cell Metabolism and Potential Therapeutic TargetsSemantic proximity Read ↗

Metabolic profiling of glioblastoma stem cells reveals pyruvate carboxylase as a critical survival factor and potential therapeutic targetSemantic proximity Read ↗

Glioblastoma Stem-Like Cells, Metabolic Strategy to Kill a Challenging TargetSemantic proximity Read ↗

Targeting cancer stem‐like cells in glioblastoma and colorectal cancer through metabolic pathwaysSemantic proximity Read ↗

Targeting cancer stem cells from a metabolic perspectiveSemantic proximity Read ↗

Energy metabolism in cancer stem cellsSemantic proximity Read ↗

The Quiescent Metabolic Phenotype of Glioma Stem CellsSemantic proximity Read ↗

The metabolic landscape of cancer stem cellsSemantic proximity Read ↗

Energy Metabolism in IDH1 Wild-Type and IDH1-Mutated Glioblastoma Stem Cells: A Novel Target for Therapy?Semantic proximity Read ↗

Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.