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Article

Gene expression profiling of breast tumor cell lines to predict for therapeutic response to microtubule-stabilizing agents.

Breast cancer research and treatment - 1 Apr 2012

Kadra Gais, Finetti Pascal, Toiron Yves, Viens Patrice, Birnbaum Daniel, Borg Jean-Paul, Bertucci François, Gonçalves Anthony

Abstract excerpt

Microtubule-targeting agents, including taxanes (Tax) and ixabepilone (Ixa), are important components of modern breast cancer chemotherapy regimens, but no molecular parameter is currently available that can predict for their efficiency. We sought to develop pharmacogenomic predictors of Tax- and Ixa-response from a large panel of human breast tumor cell lines (BTCL), then to evaluate their performance in...

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Identifiers

PMID: 21792624
DOI: 10.1007/s10549-011-1687-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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