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Construction and validation of a gene expression classifier to predict immunotherapy response in primary triple-negative breast cancer

2022-12-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Immune checkpoint inhibitors (ICI) improve clinical outcomes in triple-negative breast cancer (TNBC) patients. However, a subset of patients does not respond to treatment. Biomarkers that show ICI predictive potential in other solid tumors, such as levels of PD-L1 and the tumor mutational burden, among others, show a modest predictive performance in patients wit...

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Literature Corpus work
2fead6ce-f915-5313-9766-a45d1c4691fc
DOI
10.21203/rs.3.rs-2284514/v1
Open publication

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Construction and validation of a gene expression classifier to predict immunotherapy response in primary triple-negative breast cancerDOI 10.21203/rs.3.rs-2284514/v1
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