Article
Ontogeny of ramified CD45 cells in chicken embryo and their contribution to bursal secretory dendritic cells.
Cell and tissue research - 1 May 2017
Dóra Dávid, Fejszák Nóra, Goldstein Allan M, Minkó Krisztina, Nagy Nándor
Abstract excerpt
Embryonic tissues contain highly ramified stellate-shaped cells expressing CD45 and MHC II antigens but their origin and immunophenotype are unknown. Using staged avian embryos and cell-type-specific antibodies, we establish a detailed spatiotemporal ontogeny of cells that express CD45, the earliest marker of hematopoietic stem cells in the chick. CD45 immunostaining marks three distinct embryonic cell...
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