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Article

Fitness recovery and compensatory evolution in natural mutant lines of C. elegans.

Evolution; international journal of organic evolution - 1 Aug 2011

Estes Suzanne, Phillips Patrick C, Denver Dee R

Abstract excerpt

Deleterious mutation accumulation plays a central role in evolutionary genetics, conservation biology, human health, and evolutionary medicine (e.g., methods of viral attenuation for live vaccines). It is therefore important to understand whether and how quickly populations with accumulated deleterious mutational loads can recover fitness through adaptive evolution. We used laboratory experimental evolution with...

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Identifiers

PMID: 21790579
DOI: 10.1111/j.1558-5646.2011.01276.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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