Article
Snu56p is required for Mer1p-activated meiotic splicing.
Molecular and cellular biology - 1 Apr 2008
Balzer Richard J, Henry Michael F
Abstract excerpt
Alternative or regulated splicing can be applied to genes that are transcribed but whose products may be deleterious or unnecessary to the cell. In the yeast Saccharomyces cerevisiae, positive splicing regulation occurs during meiosis in which diploid cells divide to form haploid gametes. The Mer1 protein recruits the U1 snRNP to specific pre-mRNAs, permitting spliceosomal assembly and splicing. The mature...
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