Article
Androgen metabolic genes in prostate cancer predisposition and progression.
Frontiers in bioscience : a journal and virtual library - 1 Sept 2005
Makridakis Nick M, Buchanan Grant, Tilley Wayne, Reichardt Juergen K V
Abstract excerpt
Significant evidence implicates androgens in prostate cancer etiology. We review recent data with regard to the association between several allelic variants of specific androgen-metabolic genes and the predisposition to prostate cancer. We also review the emerging evidence regarding the role of genetic variants of these genes as well as the androgen receptor in prostate cancer progression. Based on the prostate...
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