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Article

Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease.

Neuro-Signals - 1 Jan 2011

Wu Yuncheng, Li Xinqun, Zhu Julie Xiaohong, Xie Wenjie, Le Weidong, Fan Zhen, Jankovic Joseph, Pan Tianhong

Abstract excerpt

Excessive misfolded proteins and/or dysfunctional mitochondria, which may cause energy deficiency, have been implicated in the etiopathogenesis of Parkinson's disease (PD). Enhanced clearance of misfolded proteins or injured mitochondria via autophagy has been reported to have neuroprotective roles in PD models. The fact that resveratrol is a known compound with multiple beneficial effects similar to those...

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Identifiers

PMID: 21778691
DOI: 10.1159/000328516
PMCID: PMC3699815

Genes

SIRT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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