Article

Dioscin-mediated Autophagy Alleviates Neuronal Degeneration in MPP+-treated SH-SY5Y of Parkinson's Disease Model

2022-03-03

Abstract excerpt

Autophagy is a cellular homeostatic process by which cells degrade and recycle their malfunctioned contents, and impairment in this process leads to Parkinson's disease (PD) pathogenesis. Dioscin, a steroidal saponin, has induced autophagy in several cell lines and animal models. The role of dioscin-mediated autophagy in PD remains to be investigated. Therefore, this study aims to investigate the hypothesis that d...

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Literature Corpus work: f2e8b463-0437-5aca-8423-cc02b7b49402
DOI: 10.20944/preprints202203.0063.v1

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