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Article

TDP‐43: new aspects of autoregulation mechanisms in RNA binding proteins and their connection with human disease

21 Jul 2011

Abstract excerpt

The maintenance of correct protein homeostasis ('proteostasis') is an essential activity of mammalian cells to preserve their vital properties and functions. Because of its importance, correct proteostasis is achieved by the cell in several ways and at several levels of each gene expression pathway. In many cases, mRNA-autoregulatory pathways based on a variety of feedback mechanisms have been observed to play a...

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PMID: 21777388
DOI: 10.1111/j.1742-4658.2011.08257.x

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