Characterisation of an IS1 induced mutation in the carboxy-terminal end of bacteriophage Mu transposase which affects several functional domains of the protein.

doi:10.1016/0300-9084(90)90054-k

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Article

Characterisation of an IS1 induced mutation in the carboxy-terminal end of bacteriophage Mu transposase which affects several functional domains of the protein.

Biochimie - 1 Sept 1990

Faelen M, Gama M J, Toussaint A

Abstract excerpt

We show that a mutation in bacteriophage Mu transposase (pA) which was isolated as a deletion of the C-terminal end of the protein actually consists of the replacement of the last 16 amino acids (which are mostly hydrophilic) by 26 mostly hydrophobic amino acids. This change almost completely ina...

Topics

Amino Acid Sequence
Bacteriophage mu
Base Sequence
DNA Transposable Elements
Gene Expression Regulation, Viral
Molecular Sequence Data
Mutation
Nucleotidyltransferases
Plasmids
Transposases

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