Article
Early visual sensory deficits as endophenotypes for schizophrenia: high-density electrical mapping in clinically unaffected first-degree relatives.
Archives of general psychiatry - 1 Nov 2006
Yeap Sherlyn, Kelly Simon P, Sehatpour Pejman, Magno Elena, Javitt Daniel C, Garavan Hugh, Thakore Jogin H, Foxe John J
Abstract excerpt
CONTEXT: The imperative to establish so-called endophenotypes-quantifiable measures of risk for neurological dysfunction-is a growing focus of research in schizophrenia. Electrophysiological markers of sensory processing, observable in human event-related potentials, hold great promise in this regard, lying closer to underlying physiology than descriptive clinical diagnostic tests. OBJECTIVE: Early visual...
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