Article
A Drosophila model for genetic analysis of influenza viral/host interactions.
Genetics - 1 Oct 2011
Adamson Amy L, Chohan Kultaran, Swenson Jennifer, LaJeunesse Dennis
Abstract excerpt
Influenza viruses impose a constant threat to vertebrates susceptible to this family of viruses. We have developed a new tool to study virus-host interactions that play key roles in viral replication and to help identify novel anti-influenza drug targets. Via the UAS/Gal4 system we ectopically expressed the influenza virus M2 gene in Drosophila melanogaster and generated dose-sensitive phenotypes in the eye and...
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