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A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins

20 Jul 2023

Abstract excerpt

Development of effective therapies against SARS-CoV-2 infections relies on mechanistic knowledge of virus-host interface. Abundant physical interactions between viral and host proteins have been identified, but few have been functionally characterized. Harnessing the power of fly genetics, we develop a comprehensive Drosophila COVID-19 resource (DCR) consisting of publicly available strains for conditional...

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PMID: 37480566
DOI: 10.1016/j.celrep.2023.112842

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