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Article

Modulation of respiratory dendritic cells during Klebsiella pneumonia infection.

Respiratory research - 17 Sept 2013

Hackstein Holger, Kranz Sabine, Lippitsch Anne, Wachtendorf Andreas, Kershaw Olivia, Gruber Achim D, Michel Gabriela, Lohmeyer Jürgen, Bein Gregor, Baal Nelli, Herold Susanne

Abstract excerpt

BACKGROUND: Klebsiella pneumoniae is a leading cause of severe hospital-acquired respiratory tract infections and death but little is known regarding the modulation of respiratory dendritic cell (DC) subsets. Plasmacytoid DC (pDC) are specialized type 1 interferon producing cells and considered to be classical mediators of antiviral immunity. METHOD: By using multiparameter flow cytometry analysis we have...

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Identifiers

PMID: 24044871
DOI: 10.1186/1465-9921-14-91
PMCID: PMC3848864

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