Article

GP96 drives exacerbation of secondary bacterial pneumonia following influenza A virus infection

2020-09-15

Abstract excerpt

Influenza A virus (IAV) infection predisposes the host to secondary bacterial pneumonia, known as a major cause of morbidity and mortality during influenza epidemics. Analysis of interactions between IAV-infected human epithelial cells and Streptococcus pneumoniae revealed that infected cells ectopically exhibited the endoplasmic reticulum chaperon GP96 on the surface. Importantly, efficient pneumococcal adherenc...

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Literature Corpus work: 84e99ed0-39b3-5b0c-9db3-2971969d9170
DOI: 10.1101/2020.09.14.297192

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