Article
Proteome-wide evidence for enhanced positive Darwinian selection within intrinsically disordered regions in proteins.
Genome biology - 19 Jul 2011
Nilsson Johan, Grahn Mats, Wright Anthony P H
Abstract excerpt
BACKGROUND: Understanding the adaptive changes that alter the function of proteins during evolution is an important question for biology and medicine. The increasing number of completely sequenced genomes from closely related organisms, as well as individuals within species, facilitates systematic detection of recent selection events by means of comparative genomics. RESULTS: We have used genome-wide...
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