Article
TAS2R38 bitter taste genetics, dietary vitamin C, and both natural and synthetic dietary folic acid predict folate status, a key micronutrient in the pathoaetiology of adenomatous polyps.
Food & function - 1 Aug 2011
Lucock Mark, Ng Xiaowei, Boyd Lyndell, Skinner Virginia, Wai Ron, Tang Sa, Naylor Charlotte, Yates Zoë, Choi Jeong-Hwa, Roach Paul, Veysey Martin
Abstract excerpt
Taste perception may influence dietary preferences and nutrient intakes contributing to diet-related disease susceptibility. This study examined bitter taste genetics and whether variation in the TAS2R38 gene at three polymorphic loci (A49P, V262A and I296V) could alter dietary and systemic folate levels and dietary vitamin C intake, and whether a nutrigenetic circuit existed that might link bitter taste,...
Topics
- Adenomatous Polyposis Coli
- Adult
- Aged
- Aged, 80 and over
- Ascorbic Acid
- Diet
- Erythrocytes
- Folic Acid
- Folic Acid Deficiency
- Genetic Variation
- Genotype
- Humans
- Middle Aged