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Article

Endocytic function is critical for influenza A virus infection via DC-SIGN and L-SIGN.

Scientific reports - 14 Jan 2016

Gillespie Leah, Roosendahl Paula, Ng Wy Ching, Brooks Andrew G, Reading Patrick C, Londrigan Sarah L

Abstract excerpt

The ubiquitous presence of cell-surface sialic acid (SIA) has complicated efforts to identify specific transmembrane glycoproteins that function as bone fide entry receptors for influenza A virus (IAV) infection. The C-type lectin receptors (CLRs) DC-SIGN (CD209) and L-SIGN (CD209L) enhance IAV infection however it is not known if they act as attachment factors, passing virions to other unknown receptors for...

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Source

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Identifiers

PMID: 26763587
DOI: 10.1038/srep19428
PMCID: PMC4725901

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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