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Article

Early onset HER2-positive breast cancer is associated with germline TP53 mutations.

Cancer - 15 Feb 2012

Melhem-Bertrandt Amal, Bojadzieva Jasmina, Ready Kaylene J, Obeid Elias, Liu Diane D, Gutierrez-Barrera Angelica M, Litton Jennifer K, Olopade Olufunmilayo I, Hortobagyi Gabriel N, Strong Louise C, Arun Banu K

Abstract excerpt

BACKGROUND: Germline TP53 mutations predispose to early onset breast cancer in women and are associated with Li-Fraumeni syndrome. Published data on the pathological characteristics of breast cancer among women with TP53 mutations is limited. METHODS: We retrospectively reviewed the clinical records of women who underwent genetic testing for suspected germline TP53 mutations and who were diagnosed with breast...

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Source

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Identifiers

PMID: 21761402
DOI: 10.1002/cncr.26377
PMCID: PMC3527897

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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