Article
PPARG gene promoter polymorphism is associated with non-traumatic hip fracture risk in the elderly Slovenian population: a pilot study.
Clinical biochemistry - 1 Sept 2011
Dragojevič Jana, Ostanek Barbara, Mencej-Bedrač Simona, Komadina Radko, Preželj Janez, Marc Janja
Abstract excerpt
OBJECTIVES: Peroxisome proliferator-activated receptor γ (PPARγ), an essential transcription factor for adipogenesis, has been implicated in pathogenesis of osteoporosis. The association of three single nucleotide polymorphisms in the PPARG gene with hip fracture risk, bone mineral density (BMD) and biochemical markers of bone turnover was investigated in the elderly. DESIGN AND METHODS: Six hundred sixty-seven...
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