[Association of combined polymorphisms in MIP-1α and ApoE genes with the susceptibility of inflammatory bowel disease].

Abstract excerpt

OBJECTIVE: To investigate whether the macrophage inflammatory protein 1 alpha (MIP-1α) and apolipoprotein E (ApoE) gene polymorphisms, either alone or in combination, affect the susceptibility to inflammatory bowel disease (IBD). METHODS: Genomic DNA of IBD patients with Crohn's disease (CD, n = 41) and with ulcerative colitis (UC, n = 142) and healthy controls (n = 160) was extracted and genotyped for the MIP-1α...

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