Article
[Association of IL-8 gene polymorphisms with inflammatory bowel disease in Chinese patients].
Zhonghua yi xue za zhi - 12 Jul 2011
Liang Wan-dong, Li Jin-song, Li Ke-shen, Jin Jie, Yan Jun, Yang Ji-feng, Bi Yun-tian
Abstract excerpt
OBJECTIVE: To investigate the association of interleukin 8 (IL-8) gene polymorphisms with the risks of inflammatory bowel disease (IBD). METHODS: Single nucleotide polymorphisms (SNPs) of IL-8 gene at -845 T/C, -738 T/A, -353 A/T, -251 T/A and +678 T/C were analyzed in 183 IBD patients. They included Crohn's disease (CD, n = 41), ulcerative colitis (UC, n = 142) and healthy controls (n = 160). The methods of...
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