Article
In vitro isolation of a neutralization escape mutant of equine infectious anemia virus (EIAV).
Archives of virology - 1 Jan 1990
Rwambo P M, Issel C J, Hussain K A, Montelaro R C
Abstract excerpt
A neutralization escape mutant (A/1 E) of equine infectious anemia virus was isolated after 13 passages in cell culture in the presence of serum containing antibodies to type- and group-specific determinants of EIAV envelope glycoproteins. Loss of neutralization by the selecting serum correlated...
Topics
- Animals
- Antibodies, Monoclonal
- Antibodies, Viral
- Antigens, Viral
- Cells, Cultured
- Electrophoresis, Polyacrylamide Gel
- Epitopes
- Glycoproteins
- Immunoblotting
- Infectious Anemia Virus, Equine
- Mutation
- Neutralization Tests
- Serial Passage
- Viral Envelope Proteins
