Article
In vitro isolation of a neutralization escape mutant of equine infectious anemia virus (EIAV).
Archives of virology - 1 Jan 1990
Rwambo P M, Issel C J, Hussain K A, Montelaro R C
Abstract excerpt
A neutralization escape mutant (A/1 E) of equine infectious anemia virus was isolated after 13 passages in cell culture in the presence of serum containing antibodies to type- and group-specific determinants of EIAV envelope glycoproteins. Loss of neutralization by the selecting serum correlated with loss of two epitopes in the major envelope glycoprotein gp90 of A/1 E which were present in a parallel variant...
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