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Article

Fresh surgical specimens yield breast stem/progenitor cells and reveal their oncogenic abnormalities.

Annals of surgical oncology - 1 Feb 2012

Pommier Suellen J, Hernandez Ariel, Han Esther, Massimino Kristen, Muller Patrick, Diggs Brian, Chamberlain Erin, Murphy Jennifer, Hansen Juliana, Naik Arpana, Vetto John, Pommier Rodney F

Abstract excerpt

BACKGROUND: The process by which breast cancer stem cells arise is unknown. It may be that the benign stem cells in breast tissue are transformed into malignant stem cells through the acquisition of genetic abnormalities. In this study, we collected and compared benign and malignant breast stem/progenitor cells to determine whether specific genetic abnormalities occur in breast cancer stem/progenitor cells within...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21748247
DOI: 10.1245/s10434-011-1892-z
PMCID: PMC3264874

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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