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Article

Human Papillomavirus 16 E5 Modulates the Expression of Host MicroRNAs

1 Jul 2011

Abstract excerpt

Human papillomavirus (HPV) infection is a prerequisite of developing cervical cancer, approximately half of which are associated with HPV type 16. HPV 16 encodes three oncogenes, E5, E6, and E7, of which E5 is the least studied so far. Its roles in regulating replication and pathogenesis of HPV are not fully understood. Here we utilize high-throughput screening to coordinately investigate the effect of E5 on the...

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PMID: 21747943
DOI: 10.1371/journal.pone.0021646

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