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Human papillomavirus 16 E6 modulates the expression of host microRNAs in cervical cancer

1 Aug 2015

Abstract excerpt

OBJECTIVE: Human papillomavirus (HPV) infection is a prerequisite of developing cervical cancer, approximately half of which are associated with HPV type 16. There are reports that HPV can disturb the expression pattern of host miRNAs, but its mechanism is not well understood. MATERIALS AND METHODS: In this study, we scanned 11 tumorigenesis related miRNAs in Hela cells that were overexpressed with HPV type 16 E6...

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PMID: 26384051
DOI: 10.1016/j.tjog.2014.06.007

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