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Article

Genetic clustering of European cancer patients indicates that opioid-mediated pain relief is independent of ancestry.

The pharmacogenomics journal - 1 Oct 2012

Galvan A, Fladvad T, Skorpen F, Gao X, Klepstad P, Kaasa S, Dragani T A

Abstract excerpt

The European Pharmacogenetic Opioid Study (EPOS) of a large series of European cancer patients treated with opioids was carried out to assess the influence of genetics on cancer pain relief. As response to opioid therapy was associated with the patients' country of origin, we tested whether population stratification might represent a confounding factor in the analysis of genetic control of response to opioid...

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Identifiers

PMID: 21747411
DOI: 10.1038/tpj.2011.27

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