Article
Pleiotropic skeletal and ocular phenotypes of the mouse mutation congenital hydrocephalus (ch/Mf1) arise from a winged helix/forkhead transcriptionfactor gene.
Human molecular genetics - 1 Apr 1999
Hong H K, Lass J H, Chakravarti A
Abstract excerpt
Congenital hydrocephalus is an etiologically diverse, poorly understood, but relatively common birth defect. Most human cases are sporadic with familial forms showing considerable phenotypic and etiologic heterogeneity. We have studied the autosomal recessive mouse mutation congenital hydrocephal...
Topics
- Animals
- Animals, Newborn
- Bone Development
- Bone and Bones
- Chromosome Mapping
- Contig Mapping
- Crosses, Genetic
- DNA-Binding Proteins
- Eye Abnormalities
- Female
- Forkhead Transcription Factors
- Gene Expression Regulation, Developmental