Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Defining the role of cooperation in early tumor progression.

Journal of theoretical biology - 21 Sept 2011

Krepkin Konstantin, Costa José

Abstract excerpt

Competition among cells has long been recognized as an important part of carcinogenesis. However, the role of cellular cooperation in cancer has been largely ignored. In this work, we investigated the role of cooperation in early tumor progression using a mathematical and agent-based modeling approach. We hoped to learn how the introduction of cooperative cells into a cell population would affect the dynamics of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, Tumor Suppressor
Share to Apoptosis
Share to Cell Communication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Division

Share to Cell Transformation, Neoplastic

Share to Disease Progression

Share to Neoplastic Stem Cells

Share to Oncogenes

Source

Identifiers

PMID: 21745479
DOI: 10.1016/j.jtbi.2011.06.035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Defining the role of cooperation in early tumor progression.PMID 21745479Read ↗

The role of evolutionary game theory in spatial and non-spatial models of the survival of cooperation in cancer: a review.Semantic proximity Read ↗

Evolution and phenotypic selection of cancer stem cells.Semantic proximity Read ↗

Cooperation of partially-transformed clones: an invisible force behind the early stages of carcinogenesisSemantic proximity Read ↗

Development of a population of cancer cells: Observation and modeling by a Mixed Spatial Evolutionary Games approach.Semantic proximity Read ↗

Cellular cooperation: insights from microbes.Semantic proximity Read ↗

Cell Competition Spurs Selection of Aggressive Cancer Cells.Semantic proximity Read ↗

Socializing with MYC: cell competition in development and as a model for premalignant cancer.Semantic proximity Read ↗

The role of the bi-compartmental stem cell niche in delaying cancer.Semantic proximity Read ↗

Cellular Potts Modeling of Tumor Growth, Tumor Invasion, and Tumor EvolutionSemantic proximity Read ↗

Cell Competition in Carcinogenesis.Semantic proximity Read ↗

Models of tumor-host interaction as competing populations: implications for tumor biology and treatment.Semantic proximity Read ↗

An evolutionary model of carcinogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.