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Article

Sampling HIV intrahost genealogies based on a model of acute stage CTL response.

Bulletin of mathematical biology - 1 Mar 2012

Leviyang Sivan

Abstract excerpt

Cytotoxic T lymphocytes (CTLs) play an important role in the immune response to HIV during the acute stage of infection, but the effect of CTLs on HIV intrahost genetic diversity is poorly understood. We introduce a model of CTL attack during the acute stage. Assuming this model, we develop a method to sample HIV intrahost genealogies. Using our sampling approach, we characterize the evolutionary forces that...

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Identifiers

PMID: 21739335
DOI: 10.1007/s11538-011-9670-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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