Article
Single-nucleotide polymorphism discovery by high-throughput sequencing in sorghum.
BMC genomics - 7 Jul 2011
Nelson James C, Wang Shichen, Wu Yuye, Li Xianran, Antony Ginny, White Frank F, Yu Jianming
Abstract excerpt
BACKGROUND: Eight diverse sorghum (Sorghum bicolor L. Moench) accessions were subjected to short-read genome sequencing to characterize the distribution of single-nucleotide polymorphisms (SNPs). Two strategies were used for DNA library preparation. Missing SNP genotype data were imputed by local haplotype comparison. The effect of library type and genomic diversity on SNP discovery and imputation are evaluated....
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