Article
Fine mapping of chromosome 3q22.3 identifies two haplotype blocks in ESYT3 associated with coronary artery disease in female Han Chinese.
Atherosclerosis - 1 Oct 2011
Jiang Feng, Dong Yumei, Wu Chong, Yang Xi, Zhao Ling, Guo Jian, Li Yang, Dong Jie, Zheng Gu-Yan, Cao Huiqing, Jin Lijuan, Ren Yihong, Cheng Wenli, Li Weiyang, Tian Xiao-Li, Li Xueqi
Abstract excerpt
OBJECTIVE: Genome-wide association study recently identified the chromosome 3q22.3 as a novel locus associated with coronary artery disease (CAD). This study was designed to identify the critical haplotype blocks within this region in Han Chinese populations. METHODS: We selected 1920 CAD patients and healthy participants from Han Chinese and genotyped 22 single nucleotide polymorphisms (SNPs) spanning 150...
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