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Article

Laboratory adaptation of Bordetella pertussis is associated with the loss of type three secretion system functionality.

Infection and immunity - 1 Sept 2011

Gaillard M E, Bottero D, Castuma C E, Basile L A, Hozbor D

Abstract excerpt

Although Bordetella pertussis contains and transcribes loci encoding type III secretion system (TTSS) homologues, expression of TTSS-associated proteins has been reported only for non-laboratory-adapted Irish clinical isolates. Here we confirm such a result for clinical isolates obtained from patients treated in Argentinean hospitals. Moreover, we demonstrate that the expression of TTSS-associated proteins is...

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Identifiers

PMID: 21730086
DOI: 10.1128/IAI.00136-11
PMCID: PMC3165473

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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