Article
Bordetella pertussis strains with increased toxin production associated with pertussis resurgence.
Emerging infectious diseases - 1 Aug 2009
Mooi Frits R, van Loo Inge H M, van Gent Marjolein, He Qiushui, Bart Marieke J, Heuvelman Kees J, de Greeff Sabine C, Diavatopoulos Dimitri, Teunis Peter, Nagelkerke Nico, Mertsola Jussi
Abstract excerpt
Before childhood vaccination was introduced in the 1940s, pertussis was a major cause of infant death worldwide. Widespread vaccination of children succeeded in reducing illness and death. In the 1990s, a resurgence of pertussis was observed in a number of countries with highly vaccinated populations, and pertussis has become the most prevalent vaccine-preventable disease in industrialized countries. We present...
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