Article
Characterization of Bordetella pertussis clinical isolates that do not express the tracheal colonization factor.
FEMS immunology and medical microbiology - 1 Oct 2007
van Gent Marjolein, Pierard Dénis, Lauwers Sabine, van der Heide Han G J, King Audrey J, Mooi Frits R
Abstract excerpt
Bordetella pertussis, the causative agent of whooping cough, has remained endemic and there is a resurgence in some countries despite vaccination. Bordetella pertussis produces a wide range of virulence factors which are assumed to play an important role in infection and transmission, including tracheal colonization factor (TcfA). Here we show that clinical isolates belonging to distinct lineages may lose their...
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