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Cellular Pattern of Insulin-Like Growth Factor-I (IGF-I) and Type I IGF Receptor Gene Expression in Early Organogenesis: Comparison with IGF-II Gene Expression

1 Sept 1990

Abstract excerpt

To investigate the potential role(s) of the insulin-like growth factors (IGFs) in embryogenesis, we have used in situ hybridization histochemistry to localize mRNAs for IGF-I, IGF-II, and the type I IGF receptor during an early period in rat embryonic development (embryonic days 14 and 15). IGF-I and IGF-II mRNAs were found in distinctly different patterns of cellular distribution. IGF-I mRNA was particularly...

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PMID: 2172801
DOI: 10.1210/mend-4-9-1386

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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