Article
Gene expression of the insulin-like growth factors and their receptors in human neuroblastoma cell lines.
Brain research. Molecular brain research - 1 Oct 1992
Martin D M, Yee D, Carlson R O, Feldman E L
Abstract excerpt
Insulin-like growth factors (IGF) I and II are polypeptides with both growth-promoting and insulin-like metabolic effects. The developmentally specific expression of IGF I and II in the nervous system implies a role for these growth factors in neuronal growth and differentiation. In the present study, we analyzed IGF and IGF receptor mRNA transcripts from two related human neuroblastoma cell lines, SH-SY5Y and...
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