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Article

Gene expression of the insulin-like growth factors and their receptors in human neuroblastoma cell lines.

Brain research. Molecular brain research - 1 Oct 1992

Martin D M, Yee D, Carlson R O, Feldman E L

Abstract excerpt

Insulin-like growth factors (IGF) I and II are polypeptides with both growth-promoting and insulin-like metabolic effects. The developmentally specific expression of IGF I and II in the nervous system implies a role for these growth factors in neuronal growth and differentiation. In the present study, we analyzed IGF and IGF receptor mRNA transcripts from two related human neuroblastoma cell lines, SH-SY5Y and...

Topics

Cell Differentiation
Cell Division
DNA Probes
Gene Expression
Humans
Insulin-Like Growth Factor I
Insulin-Like Growth Factor II
Neuroblastoma
Neurons
Phenotype
RNA, Messenger

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptor, IGF Type 1

Receptor, IGF Type 2

Transcription, Genetic

Tumor Cells, Cultured

Source

Identifiers

PMID: 1331680
DOI: 10.1016/0169-328x(92)90114-q

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1331680-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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