Fibroblasts retain their tissue phenotype when grown in three-dimensional collagen gels.

doi:10.1016/0014-4827(91)90394-a

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Article

Fibroblasts retain their tissue phenotype when grown in three-dimensional collagen gels.

Experimental cell research - 1 Aug 1991

Doane K J, Birk D E

Abstract excerpt

Fibroblasts are responsible for the synthesis, assembly, deposition, and organization of extracellular matrix molecules, and thus determine the morphology of connective tissues. Deposition of matrix molecules occurs in extracellular compartments, where the sequential stages are under cellular con...

Topics

Animals
Cell Division
Cells, Cultured
Chick Embryo
Collagen
Cornea
Culture Media
Fibroblasts
Gels
Microscopy, Fluorescence
Phenotype
Skin
Tendons

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