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Article

Pan-cancer mapping of differential protein-protein interactions.

Scientific reports - 24 Feb 2020

Gulfidan Gizem, Turanli Beste, Beklen Hande, Sinha Raghu, Arga Kazim Yalcin

Abstract excerpt

Deciphering the variations in the protein interactome is required to reach a systems-level understanding of tumorigenesis. To accomplish this task, we have considered the clinical and transcriptome data on >6000 samples from The Cancer Genome Atlas for 12 different cancers. Utilizing the gene expression levels as a proxy, we have identified the differential protein-protein interactions in each cancer type and...

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Identifiers

PMID: 32094374
DOI: 10.1038/s41598-020-60127-x
PMCID: PMC7039988

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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