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Article

Lactose transport mutants of Escherichia coli resistant to inhibition by the phosphotransferase system.

Biochimica et biophysica acta - 2 Nov 1990

Wilson T H, Yunker P L, Hansen C L

Abstract excerpt

The lactose carrier activity of Escherichia coli is inhibited by the binding of dephosphorylated glucose enzyme III. Saier et al. ((1978) J. Bacteriol. 133, 1358-1367) isolated lacY mutants that escaped this inhibition. This communication reports the cloning and sequencing of one of the Saier mutants and the isolation, cloning and sequencing of another similar mutant. Both mutations resulted in amino acid...

Topics

Binding Sites
Biological Transport
Carrier Proteins
Cloning, Molecular
Cytoplasm
Drug Resistance, Microbial
Escherichia coli
Lactose
Methylglucosides
Models, Biological
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phosphotransferases

Source

Identifiers

PMID: 2171650
DOI: 10.1016/0005-2736(90)90443-r

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2171650-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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