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KIR-Ligand Mismatches Are Associated With Reduced Long-Term Graft Survival in HLA-Compatible Kidney Transplantation

30 Jun 2011

Abstract excerpt

Natural killer (NK) cells are cytotoxic lymphocytes of the innate immune system with the ability to detect HLA class I disparities via killer-cell immunoglobulin-like receptors (KIR). To test whether such KIR-ligand mismatches contribute to the rejection of human solid allografts, we did a retrospective cohort study of 397 HLA-DR-compatible kidney transplantations and determined the KIR and HLA genotypes of...

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Share to Immune Cell Function and Interaction
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PMID: 21714849
DOI: 10.1111/j.1600-6143.2011.03621.x

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KIR-Ligand Mismatches Are Associated With Reduced Long-Term Graft Survival in HLA-Compatible Kidney TransplantationPMID 21714849Read ↗

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