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Article

Intratumoral lymphocyte density in serous ovarian carcinoma is superior to ERCC1 expression for predicting response to platinum-based therapy.

Virchows Archiv : an international journal of pathology - 1 Aug 2011

Bösmüller Hans, Haitchi-Petnehazy Sophie, Webersinke Gerald, Marschon Renate, Roithmeier Franz, Stummvoll Wolfgang, Fehm Tanja, Klier-Richter Margit, Bonzheim Irina, Staebler Annette, Fend Falko

Abstract excerpt

Intratumoral immune cells and ERCC1 expression are likely to play a role in the response of ovarian carcinoma to chemotherapy, but their impact on therapy outcome is still unclear. Therefore, 41 cases of optimally resected high grade serous ovarian carcinomas were examined retrospectively for stromal and intraepithelial lymphocyte populations and ERCC1 status in relation to response to platinum-based therapy....

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Share to Antineoplastic Agents
Share to Cystadenocarcinoma, Serous

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to Endonucleases

Share to Lymphocytes, Tumor-Infiltrating

Share to Ovarian Neoplasms

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Source

Identifiers

PMID: 21713364
DOI: 10.1007/s00428-011-1110-1

Genes

ERCC1
TIA1
FOXP3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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