Article
Identification and characterization of a regulated promoter element in the epidermal growth factor receptor gene.
Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 1990
Hudson L G, Thompson K L, Xu J, Gill G N
Abstract excerpt
We have identified a 36-base-pair proximal element (-112 to -77 relative to the AUG translation initiation codon) in the epidermal growth factor receptor 5' region that functions as a promoter; mediates inductive responses to epidermal growth factor, phorbol 12-myristate 13-acetate, and cyclic AMP; and acts in an orientation-independent manner. This region functions as an enhancer when transferred to a...
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