Article
Myocilin mt1 promoter polymorphism in Turkish patients with primary open angle glaucoma.
Molecular vision - 2 Nov 2005
Ozgül Riza Köksal, Bozkurt Banu, Orcan Serkan, Bulur Burçin, Bagiyeva Sefayet, Irkeç Murat, Ogüş Ay
Abstract excerpt
PURPOSE: To evaluate the association of the myocilin gene promoter variant -1000C>G (MYOC.mt1) with primary open angle glaucoma (POAG) and its possible role on the phenotype and the severity of glaucoma in Turkish patients. METHODS: Eighty eight POAG patients and 123 healthy subjects were included in the study. All subjects were genotyped by PCR-RFLP. Allele and genotype frequencies between healthy subjects and...
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